Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity linked to bortezomib, a proteasome inhibitor Employed in the cure of numerous myeloma. Its synthesis or study is crucial for making sure the purity and basic safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise sorts of most cancers, which include Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their examine is essential for optimizing the generation procedure and guaranteeing substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilised to take care of Lenvatinib Impurity b breast most cancers, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the treatment method of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug successful in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal cancer Androsta-5 and small cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have several purposes, including antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for form two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of varied gluconic acid derivatives, which are Employed in food, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication applied to control variety 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).